Drug Discovery and Generating Impact

Synthetic Natural Products (SynNP)
The SynNP project aims to apply synthetic biology to the discovery and design of new antibiotics against tuberculosis and other infectious diseases. Based on a large Bio Synthetic Gene (BSG) library and yeast promoter library (YeastFab), we are able to mix and match BSGs to assemble diversified synthetic pathway circuits, which can produce chemical libraries for the treatment of tuberculosis infection. With further high-throughput screening, we aim to discover new treatments and improve the yield of medicines against tuberculosis.